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M4603

Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-α-Melanocyte Stimulating Hormone Amide Fragment 4-10

≥95% (HPLC), Melanocortin-4 receptor antagonist

Synonym(s):

SHU9119

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About This Item

Empirical Formula (Hill Notation):
C54H71N15O9
Molecular Weight:
1074.24
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
MFCD02093607
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Product Name

Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-α-Melanocyte Stimulating Hormone Amide Fragment 4-10, ≥95% (HPLC)

Quality Segment

200

assay

≥95% (HPLC)

UniProt accession no.

P01189

storage temp.

−20°C

Gene Information

human ... POMC(5443)

Biochem/physiol Actions

Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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