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7-Methylguanosine

Name: 7-Methylguanosine
Brand: SIGMA

≥90%, synthetic, powder

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₅N₅O₅

CAS Number:

20244-86-4

Molecular Weight:

297.27

NACRES:

NA.51

PubChem Substance ID:

24896562

UNSPSC Code:

41106305

MDL number:

MFCD16661197

Beilstein/REAXYS Number:

3713683

Assay:

≥90%

Biological source:

synthetic

Form:

powder

Solubility:

water: 50 mg/mL, clear to hazy, colorless to faintly yellow

Storage temp.:

2-8°C

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Properties

Product Name

7-Methylguanosine, ≥90%

biological source

synthetic

Quality Segment

200

assay

≥90%

form

powder

solubility

water: 50 mg/mL, clear to hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13

InChI

1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1

InChI key

OGHAROSJZRTIOK-KQYNXXCUSA-N

Description

General description

7-Methylguanosine structure is also referred to as a cap. It is located on the 5′ end of the cytoplasmic mRNA.

Application

7-Methylguanosine has been used in the removal of residual phosphates from pre rigor solution, phosphate mop system and phosphorous standard solution.

Biochem/physiol Actions

7-Methylguanosine is involved in the processing of a cap-dependent translational process of mRNA. It is also involved in protecting the mRNA from degradation due to ribonucleases and mediate nuclear export. 7-Methylguanosine also permits the recruitment of ribosome.

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This Item	M5883	A3401	F5130
Sigma-Aldrich M0627 7-Methylguanosine	Sigma-Aldrich M5883 7-Methylguanosine 5′-diphosphate sodium salt	Sigma-Aldrich A3401 Ala-Ala-Phe-7-amido-4-methylcoumarin	Sigma-Aldrich F5130 5-Fluorouridine
description ≥90%	description ≥92.5%	description protease substrate	description proapoptotic anitproliferative plant growth regulator
biological source synthetic	biological source synthetic (organic)	biological source -	biological source synthetic (organic)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
form powder	form powder	form powder	form powder
assay ≥90%	assay ≥92.5%	assay ≥98% (TLC)	assay ≥99% (HPLC)
solubility water: 50 mg/mL, clear to hazy, colorless to faintly yellow	solubility water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow	solubility ethanol: 20 mg/mL, clear, colorless to light yellow	solubility water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. -

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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