The solubility of this material in DMSO is not determined. However, sources state that Linoleic acid (CAS 60-33-3) is soluble in DMSO at concentrations of at least 43 to 90 mg/mL (approx. 154 to 321 mM). Please note that this information has not been validated internally.
L1012
Linoleic acid
liquid, BioReagent, suitable for cell culture
Synonym(s):
cis-9,cis-12-Octadecadienoic acid
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About This Item
Linear Formula:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
CAS Number:
Molecular Weight:
280.45
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12352211
EC Number:
200-470-9
MDL number:
Beilstein/REAXYS Number:
1727101
Pricing and availability is not currently available.
biological source
plant (Safflower oil)
Quality Segment
product line
BioReagent
assay
≥98%
form
liquid
technique(s)
cell culture | mammalian: suitable
refractive index
n20/D 1.466 (lit.)
bp
229-230 °C/16 mmHg (lit.)
mp
−5 °C (lit.)
solubility
NaOH: 1 M, ethanol: soluble
density
0.902 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
InChI key
OYHQOLUKZRVURQ-HZJYTTRNSA-N
Gene Information
human ... SOAT1(6646), SOAT2(8435)
General description
Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.
Application
Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.
Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).
Biochem/physiol Actions
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .
Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.
Packaging
Sealed ampule.
1 of 1
This Item | |||
|---|---|---|---|
| description liquid, BioReagent, suitable for cell culture | description analytical standard | description ≥95%, FG | description natural (US), ≥95%, FG |
| assay ≥98% | assay ≥98.0% (GC) | assay ≥95% | assay ≥95% |
| technique(s) cell culture | mammalian: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) - |
| biological source plant (Safflower oil) | biological source - | biological source synthetic | biological source (Sunflower seed) |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| form liquid | form - | form - | form - |
| solubility NaOH: 1 M, ethanol: soluble | solubility - | solubility - | solubility - |
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Can I resuspend in DMSO? If so, what is the recommended concentration to resuspend at?
1 answer-
Helpful?
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What volume does the 100mg come dissolved in, i.e., what is the initial concentration? I have 50uL of liquid left, how can I figure out how many mg that is?
1 answer-
Linoleic Acid is provided as a neat, pure liquid. The initial volume can be calculated by dividing the mass by the density. For example, a 100 mg bottle will contain 0.1g divided by 0.902 g/mL, which equals 110 µL.
Helpful?
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What is the concentration (g/L) of the solution
1 answer-
This product is a neat or pure liquid and has not been diluted. The material has a density of 0.902 g/mL and a minimum purity of 99%.
Helpful?
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