L0906
L-α-Lysophosphatidylcholine from Glycine max (soybean)
≥99%, lyophilized powder
Synonym(s):
1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|
About This Item
Pricing and availability is not currently available.
biological source
soybean
Quality Level
description
zwitterionic
assay
≥99%
form
lyophilized powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Biochem/physiol Actions
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
Packaging
Packaged under Argon.
Preparation Note
Prepared by the action of phospholipase A on soybean L-α-phosphatidylcholine (P 6263).
1 of 1
This Item | |||
|---|---|---|---|
| form lyophilized powder | form - | form - | form powder |
| assay ≥99% | assay - | assay - | assay ≥99% |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| biological source soybean | biological source - | biological source - | biological source egg yolk |
| description zwitterionic | description - | description - | description zwitterionic |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level 200 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
E de Lamirande et al.
Journal of andrology, 33(5), 1025-1035 (2012-03-10)
Capacitation (CAP) and acrosome reaction (AR) are sequential processes of sperm activation. Beside the known ionic, membrane, and transduction events and final release of proteolytic enzymes that help sperm movement toward the egg, chromatin changes, such as a physiological remodeling
Guillaume Bach et al.
Clinical and vaccine immunology : CVI, 17(3), 429-438 (2010-01-15)
Improving vaccine immunogenicity by developing new adjuvant formulations has long been a goal of vaccinologists. It has previously been shown that a natural mix of lysophosphatidylcholine (LPC) from chicken eggs promotes mature dendritic cell (DC) generation in vitro and primes
Hui-Ching Tseng et al.
Cellular and molecular life sciences : CMLS, 75(24), 4599-4617 (2018-09-20)
Lysophosphatidylcholine (LysoPC) has been shown to induce the expression of inflammatory proteins, including cyclooxygenase-2 (COX-2) and interleukin-6 (IL-6), associated with cardiac fibrosis. Here, we demonstrated that LysoPC-induced COX-2 and IL-6 expression was inhibited by silencing NADPH oxidase 1, 2, 4
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L0906-100MG | 04061835545896 |
| L0906-500MG | 04061832793795 |
| L0906-25MG | 04061832793788 |