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Key Documents

G0503

Sigma-Aldrich

Karaya gum

Synonym(s):

Gum karaya from sterculia tree, Tragacanth Indian

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

plant fluids (Gum karaya)

form

powder

color

faint yellow to brown

storage temp.

room temp

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Application

Karaya gum may be used for the development of gastro intestinal tract drug delivery vehicles, mucoadhesive sustained release drug delivery and noneffervescent floating drug delivery systems in combination with alginate.

Other Notes

Believed to be a partially acetylated polymer of galactose, rhamnose, and glucuronic acid with a M.W. of approx. 9,500,000.
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anil Getyala et al.
Current drug delivery, 10(5), 620-629 (2013-01-05)
The aim of the work is to modify the solubility and bioavailability of Losartan potassium, by employing noneffervescent floating drug delivery (tablet dosage forms). Non-effervescent systems are a type of floating drug delivery systems, that have been used to boost
Baljit Singh et al.
International journal of biological macromolecules, 43(2), 142-150 (2008-05-27)
The present paper deals with the modification of the sterculia gum with methacrylic acid (MAAc) to hydrogels for use in drug delivery. The hydrogels were characterized by SEMs, FTIR and swelling studies. The release dynamics of model anti-ulcer drug (ranitidine
S Singh et al.
Current drug delivery, 4(4), 269-275 (2007-11-06)
The present investigation concerns the development of floating matrix tablets of metoclopramide hydrochloride (MHCl) for improving its bioavailability by prolonging gastric residence time. Floating matrix tablets (FMT) of MHCl were prepared using the polymers guar gum (GG), karaya gum (KG)
Sadia Afrose et al.
Nutrition research (New York, N.Y.), 29(5), 350-354 (2009-06-27)
Different sources of saponins are known to have hypocholesterolemic activity with varying degrees of efficacy. We hypothesize that karaya root saponin would efficiently reduce cholesterol. The aim of this study is to examine the comparative hypocholesterolemic effect of karaya root
Calum R Park et al.
Drug development and industrial pharmacy, 30(6), 609-617 (2004-08-03)
Some naturally occurring biocompatible materials were evaluated as mucoadhesive controlled release excipients for buccal drug delivery. A range of tablets were prepared containing 0-50% w/w xanthan gum, karaya gum, guar gum, and glycol chitosan and were tested for swelling, drug

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