E0377

D-Erythrose 4-phosphate sodium salt

≥50% (TLC)

• Synonym(s): 4-Phospho-D-erythrose sodium salt
• Empirical Formula (Hill Notation): C₄H₈NaO₇P
• CAS Number: 103302-15-4
• Molecular Weight: 222.07
• MDL number: MFCD32062525
• UNSPSC Code: 12352201
• NACRES: NA.25

Properties

• Quality Segment: 100
• assay: ≥50% (TLC)
• form: powder
• color: white to off-white
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: [Na+].[H]C(=O)[C@H](O)[C@H](O)COP(O)([O-])=O
• InChI: 1S/C4H9O7P.Na/c5-1-3(6)4(7)2-11-12(8,9)10;/h1,3-4,6-7H,2H2,(H2,8,9,10);/q;+1/p-1/t3-,4+;/m0./s1
• InChI key: KKDBADMPNGAKHM-RFKZQXLXSA-M

Description

Application

D-Erythrose 4-phosphate (E4P) is used as a substrate to identify, differentiate and characterize 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) aldolase(s) and 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) synthase(s) that initiate the shikimate pathway in microorganisms and plants.[1] It may be used as a substrate to identify, differentiate and characterize glyceraldehyde-3-phosphate dehydrogenase(s) (GAPDH) involved in surface antigen and virulence factor development in pathogenic microorganisms.[2] E4P may be used in malaria research as an inhibitor of the PfPdx1 component of the PLP (pyridoxal 5′-phosphate) synthase enzymatic complex responsible for the de novo synthesizes vitamin B6 in Plasmodium falciparum.[3]

Biochem/physiol Actions

Erythrose 4-phosphate is an intermediate in the penntose phosphate pathway, as well as the biosynthesis of phenylalanine, tyrosine, tryptophan and metabolism of vitamin B6.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable