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About This Item
Empirical Formula (Hill Notation):
C10H14N5O7P
CAS Number:
Molecular Weight:
347.22
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥98% (HPLC)
Biological source:
yeast
Form:
powder
Solubility:
water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
Storage temp.:
−20°C
Product Name
Adenosine 3′-monophosphate sodium salt, from yeast
biological source
yeast
Quality Level
assay
≥98% (HPLC)
form
powder
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
storage temp.
−20°C
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(CO)C(OP(O)(O)=O)C3O
InChI
1S/C10H14N5O7P.Na.H/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;
InChI key
SHIVFKVYHYZMPS-UHFFFAOYSA-N
General description
Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from the hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits the proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP, and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.
Application
Adenosine 3′-monophosphate sodium salt has been used as a marker in thin-layer chromatography (TLC).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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2′-AMP and 3′-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
Jackson EK, Gillespie DG, Dubey RK.
Journal of Pharmacology and Experimental Therapeutics, 337, 4440450-4440450 (2011)
J Martinez et al.
The Journal of biological chemistry, 275(31), 24222-24230 (2000-05-10)
We have previously identified a HeLa cell 3' exonuclease specific for degrading poly(A) tails of mRNAs. Here we report on the purification and identification of a calf thymus 54-kDa polypeptide associated with a similar 3' exonuclease activity. The 54-kDa polypeptide
Feng Rao et al.
Biochemical and biophysical research communications, 398(3), 500-505 (2010-07-06)
The recent report of 2',3'-cAMP isolated from rat kidney is the first proof of its biological existence, which revived interest in this mysterious molecule. 2',3'-cAMP serves as an extracellular adenosine source, but how it is degraded remains unclear. Here, we
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A0386-500MG | 04061833257852 |
| A0386-100MG | 04061833257838 |
| A0386-1G | 04061826687659 |