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86694

Sigma-Aldrich

Tetraethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

Synonym(s):

C12E4, Dodecyl tetraethylene glycol ether, Dodecyltetraglycol

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)4OH
CAS Number:
5274-68-0
Molecular Weight:
362.54
Beilstein:
1791369
EC Number:
226-097-1
MDL number:
MFCD00043063
UNSPSC Code:
12161900
PubChem Substance ID:
57653173
NACRES:
NA.25

description

non-ionic

product line

BioXtra

Assay

≥98.0% (GC)

form

liquid

mol wt

362.54 g/mol

refractive index

n20/D 1.450-1.454

density

0.946 g/mL at 20 °C (lit.)

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

InChI key

WPMWEFXCIYCJSA-UHFFFAOYSA-N

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General description

Tetraethylene glycol monododecyl ether (C12E4) is a nonionic surfactant. It is used as a stabilizer in several phase behavior and evaporation studies. This polyoxyethylated lauryl ether surfactant is a water-soluble surfactant.

Application

Tetraethylene glycol monododecyl ether (C12E4) has been used:


  • as a water-soluble surfactant in computational and physical experiments to report the post-deposition motion of the surfactant front and the deformation of the subphase surface using Marangoni flow and capillary waves
  • to study its mixed micellization and interfacial properties in the absence and presence of sodium propionate
  • to investigate the phase transformation of C12E4 aqueous solutions by Rayleigh light scattering (RLS) when adopting different heating ways

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315,H319,H335,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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USP

USP

1372468

Polyoxyl 23 lauryl ether

Ethylene glycol monododecyl ether BioXtra, ≥99.0% (GC)

Sigma-Aldrich

03819

Ethylene glycol monododecyl ether

Aijaz A Dar et al.
Journal of colloid and interface science, 298(1), 395-405 (2005-12-28)
Mixed micelle formation and interfacial properties of aqueous binary surfactant combinations of dodecyltrimethylammonium bromide (C12TAB) and tetraethyleneglycol mono-n-dodecyl ether (C12E4) at 30 degrees C in absence and presence of sodium propionate (NaPr) have been investigated. The critical micelle concentration, aggregation
Jun Sawayama et al.
Langmuir : the ACS journal of surfaces and colloids, 27(14), 8653-8658 (2011-06-09)
By mixing a small volume of THF containing guanosine derivative 1 and tetraethylenegrycol dodecyl ether (TEGDE) with water and subsequently removing TEGDE by gel permeation chromatography, micrometer-sized giant unilamellar vesicles (GUV) of 1 were successfully prepared. The vesicle membrane was
N Taulier et al.
Biophysical journal, 78(2), 857-865 (2000-02-02)
We have used a lamellar phase made of a nonionic surfactant, dodecane and water, as a model membrane to investigate its interactions with macromolecular inclusions bringing together two membranes, i.e., acting as macromolecular snaps. In systems devoid of inclusions, the
M Adachi et al.
Biotechnology and bioengineering, 58(6), 649-653 (1999-04-01)
Selective separation of trypsin from a mixture involving many kinds of contaminating proteins, i.e., pancreatin, was achieved using trypsin inhibitor immobilized in the reverse micelles, which were composed of a nonionic surfactant, tetra-oxyethylene monodecylether. To determine the efficient operations throughout
D J Kerr et al.
European journal of cancer & clinical oncology, 23(9), 1315-1322 (1987-09-01)
The effects of a non-ionic polyoxyethylated lauryl ether surfactant (Brij 30) on monolayer uptake and spheroid penetration of adriamycin have been studied. Co-incubation of adriamycin with Brij 30 increases intracellular adriamycin levels by 2-3-fold. Although, in the concentrations used, Brij
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