T5500
2-Thiobarbituric acid
≥98%
Synonym(s):
4,6-Dihydroxy-2-mercaptopyrimidine, 4,6-Dihydroxypyrimidine-2-thiol, TBA
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About This Item
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Quality Level
Assay
≥98%
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
mp
245 °C (dec.) (lit.)
SMILES string
O=C1CC(=O)NC(=S)N1
InChI
1S/C4H4N2O2S/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)
InChI key
RVBUGGBMJDPOST-UHFFFAOYSA-N
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General description
2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen.
Application
2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay.
Biochem/physiol Actions
2-Thiobarbituric acid (TBA) is useful to quantitate lipopolysaccharides, carrageenan, and sialic acids. It is also used to detect lipid hydroperoxides and lipid oxidation. It has applications in the field of medicine and biochemistry. TBA may possess the ability to prevent metal corrosion.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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