RDD040

Sodium dodecyl sulfate

BioReagent, Molecular Biology, ≥98.5% (GC), free-flowing, Redi-Dri^™

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• NACRES: NA.25
• UNSPSC Code: 12161900
• Beilstein/REAXYS Number: 3599286
• MDL number: MFCD00036175

Properties

• grade: Molecular Biology
• Quality Segment: 100
• description: anionic
• product line: BioReagent, Redi-Dri^™
• assay: ≥98.5% (GC)
• quality: free-flowing
• mol wt: micellar 18,000
• aggregation number: 62
• technique(s): electrophoresis: suitable
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C
• solubility: water: soluble
• anion traces: chloride (Cl^-): ≤500 ppm, phosphate (PO₄^3-): ≤10 ppm
• cation traces: heavy metals (as Pb): ≤10 ppm
• absorption: ≤0.1 at 260 at 3%, ≤0.1 at 280 at 3%
• HLB: 40
• suitability: suitable for electrophoresis
• foreign activity: DNase, RNase, none detected
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Sodium dodecyl sulfate (SDS) is an amphipathic detergent commonly used for denaturing proteins. SDS has a long-chain aliphatic group, with negatively charged sulfate groups that coat the surface of proteins, causing them to lose their quaternary structure.

Application

Anionic detergent

Sodium dodecyl sulfate has been used:

• in chromatin immunoprecipitation
• in SDS-polyacrylamide gel electrophoresis (SDS-PAGE)
• as a component of radioimmunoprecipitation assay buffer for immunoblotting

Analysis Note

Tested for use in denatured polyacrylamide gel electrophoresis.

Other Notes

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Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H228,H302 + H332,H315,H318,H335,H412
• pcodes: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 4.1B - Flammable solid hazardous materials
• wgk: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C