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92986

Supelco

N-Propionylglycine

analytical standard

Synonym(s):

2-(Propionylamino)acetic acid, N-(1-Oxopropyl)glycine, NSC 158539, Propionyl glycine

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About This Item

Empirical Formula (Hill Notation):
C5H9NO3
CAS Number:
Molecular Weight:
131.13
Beilstein:
1759032
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

OC(CNC(CC)=O)=O

InChI

1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)

InChI key

WOMAZEJKVZLLFE-UHFFFAOYSA-N

Biochem/physiol Actions

Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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