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34041

Supelco

Orbifloxacin

VETRANAL®, analytical standard

Synonym(s):

1-Cyclopropyl-5,6,8-trifluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1-piperazinyl)-4-oxo-quinoline-3-carboxylic acid, Orbax

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About This Item

Empirical Formula (Hill Notation):
C19H20F3N3O3
CAS Number:
113617-63-3
Molecular Weight:
395.38
MDL number:
MFCD00864858
UNSPSC Code:
41116107
PubChem Substance ID:
329754776
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

C[C@@H]1CN(C[C@H](C)N1)c2c(F)c(F)c3C(=O)C(=CN(C4CC4)c3c2F)C(O)=O

InChI

1S/C19H20F3N3O3/c1-8-5-24(6-9(2)23-8)17-14(21)13(20)12-16(15(17)22)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6H2,1-2H3,(H,27,28)/t8-,9+

InChI key

QIPQASLPWJVQMH-DTORHVGOSA-N

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General description

Orbifloxacin is an antibacterial fluoroquinolone derivative,for use in small animals such as dogs and cats.

Application

Orbifloxacin may be used as a reference standard in the estimation of orbifloxacin in pharmaceutical formulations using ultraviolet spectrophotometric technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8452
BCCG7170
BCBZ3295
BCBV2017
SZBD304XV

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Sigma-Aldrich

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Kirk's Current Veterinary Therapy: Small animal practice (2009)
Development and validation of UV spectrophotometric method for orbifloxacin assay and dissolution studies.
Cazedey LCE and Salgado NRH
Brazilian Journal of Pharmaceutical Sciences , 50(3), 457-465 (2014)
Photodegradation products of a new antibacterial fluoroquinolone derivative, orbifloxacin, in aqueous solution.
Morimura T, et al.
Chemical & Pharmaceutical Bulletin, 45(2), 373-377 (1997)
Cinzia Civitareale et al.
Rapid communications in mass spectrometry : RCM, 32(21), 1831-1842 (2018-06-27)
Carry-over is an undesirable contamination from medicated to non-medicated during the production of feedingstuffs. In 2014 the European Parliament and the Council started working to produce a new regulatory act that will fix tolerable levels of drugs by carry-over in
Tao Wang et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(5), 1218-1225 (2015-04-04)
Surgical hindlimb ischemia (HLI) in mice has become a valuable preclinical model to study peripheral arterial disease. We previously identified that the different phenotypic outcomes after HLI across inbred mouse strains is related to a region on the short arm
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