8.52375

Fmoc-hLys(Boc)-OH

Novabiochem^®

• Synonym(s): Fmoc-hLys(Boc)-OH, N-α-Fmoc-N-ω-t.-Boc-L-homolysine
• Empirical Formula (Hill Notation): C₂₇H₃₄N₂O₆
• CAS Number: 194718-17-7
• Molecular Weight: 482.57
• MDL number: MFCD01860606
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Segment: 200
• product line: Novabiochem^®
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: amine
• storage temp.: 2-8°C
• SMILES string: N([C@@H](CCCCCNC(=O)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C27H34N2O6/c1-27(2,3)35-25(32)28-16-10-4-5-15-23(24(30)31)29-26(33)34-17-22-20-13-8-6-11-18(20)19-12-7-9-14-21(19)22/h6-9,11-14,22-23H,4-5,10,15-17H2,1-3H3,(H,28,32)(H,29,33)(H,30,31)/t23-/m0/s1
• InChI key: CLFMIWUWBOOJLY-QHCPKHFHSA-N

Description

General description

This homolog of lysine has been used to modulate ion-pairing interactions between Lys and enzyme carboxylate groups in SAR studies ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] K. J. Kennedy, et al. (1997) Bioorg. Med. Chem. Lett., 7, 1937.

Application

Fmoc-hLys(Boc)-OH can be used as a building block in the solid phase peptide synthesis.

Analysis Note

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable