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4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide

Name: 4-Methylumbelliferyl-N-acetyl-&#946;-D-glucosaminide
Brand: MM

≥98% (TLC), fluorogenic N-acetyl-β-D-glucosaminidase substrate, crystalline solid

Synonym(s):

4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide, 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₁NO₈

CAS Number:

37067-30-4

Molecular Weight:

379.36

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00150977

Assay:

≥98% (TLC)

Form:

crystalline solid

Storage condition:

OK to freeze, desiccated, protect from light

Pricing and availability is not currently available.

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Properties

Product Name

4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide, Ultrasensitive, fluorogenic substrate for assays of N-acetyl-β-D-glucosaminidase.

Quality Segment

100

assay

≥98% (TLC)

form

crystalline solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated, protect from light

solubility

methanol: soluble, water: soluble

fluorescence

λ_ex 360 nm, λ_em 440 nm

shipped in

ambient

storage temp.

−20°C

SMILES string

N([C@@H]1[C@H]([C@@H]([C@H](OC1Oc2cc3c(cc2)C(=CC(=O)O3)C)CO)O)O)C(=O)C

InChI

1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18?/m1/s1

InChI key

QCTHLCFVVACBSA-XWEABGILSA-N

Description

General description

Ultrasensitive, fluorogenic substrate for assays of N-acetyl-β-D-glucosaminidase (excitation maximum: 360 nm; emission maximum: 440 nm).

Preparation Note

Unstable in aqueous solutions. Reconstitute just prior to use.

Unstable in solution; reconstitute just prior to use.

Other Notes

Chen, K.S., et al. 1994. Electrophoresis 15, 662.
Leaback, D.H., and Walker, P.G. 1961. Biochem. J.78, 151.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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This Item	474426	474422	474500
Sigma-Aldrich 474502 4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide	Sigma-Aldrich 474426 4-Methylumbelliferyl-α-D-glucopyranoside	Sigma-Aldrich 474422 4-Methylumbelliferyl-α-D-galactopyranoside	Sigma-Aldrich 474500 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide
description Ultrasensitive, fluorogenic substrate for assays of N-acetyl-β-D-glucosaminidase.	description Substrate for fluorogenic assay of α-glucosidase. Has been used in studies of Pompe disease.	description Substrate for the fluorogenic assay of α-D-galactosidase.	description Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.
assay ≥98% (TLC)	assay ≥99% (HPLC)	assay ≥98% (HPLC)	assay -
form crystalline solid	form solid	form solid	form solid
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. 10-30°C	storage temp. −20°C	storage temp. 10-30°C
solubility methanol: soluble, water: soluble	solubility methanol: soluble	solubility DMF: 50 mg/mL	solubility DMSO: soluble, DMF: soluble

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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