394111

BIS-TRIS propane

ULTROL^® Grade, >98% (titration), non-zwitterionic buffer useful in pH range 6.3-9.5

• Synonym(s): BIS-Tris Propane, ULTROL^® Grade, 1,3- bis[ tris(Hydroxymethyl)methylamino]propane, 1,3-bis[tris(Hydroxymethyl)methylamino]propane
• Empirical Formula (Hill Notation): C₁₁H₂₆N₂O₆
• CAS Number: 64431-96-5
• Molecular Weight: 282.33
• UNSPSC Code: 12161705
• NACRES: NA.25
• MDL number: MFCD00004689

Properties

• Quality Segment: 100
• assay: >98% (titration)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• pKa (20 °C): 6.8
• solubility: water: 1 M
• cation traces: heavy metals: <1 ppm
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: N(C(CO)(CO)CO)CCCNC(CO)(CO)CO
• InChI: 1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
• InChI key: HHKZCCWKTZRCCL-UHFFFAOYSA-N

Description

General description

A non-zwitterionic buffer (Absorbance: <0.08 at 260 nm, 1.0 M, H₂O) that is useful near physiological pH (6.3-9.5). Has a pK_a of 6.8 at 25°C.

A non-zwitterionic buffer that is useful in the pH 6.3-9.5 range. Has pK_as of 6.8 (pK_a1) and 9.0 (pK_a2).

Absorbance (1.0 M, H₂O, 260 nm): <0.08.

Application

• Comparing solution-gate and bottom-gate nanowire field-effect transistors on pH sensing with different salt concentrations and surface modifications.: BIS-TRIS propane is used as a buffering agent in the development of nanowire field-effect transistors for pH sensing. The research demonstrates its effectiveness in enhancing the sensitivity and stability of these biosensors under varying conditions (Hu et al., 2024).


• Laser-induced tuning of graphene field-effect transistors for pH sensing.: This study employs BIS-TRIS propane as a buffering solution to optimize the performance of graphene field-effect transistors in pH sensing applications. The findings highlight the role of BIS-TRIS propane in achieving precise tuning of sensor responses (Lampinen et al., 2023).


• Elucidating the exchange interactions in a {Gd(III)Cu(II)(4)} propellor.: BIS-TRIS propane is utilized as a buffer in the investigation of exchange interactions in complex metal assemblies. The study provides insights into the magnetic properties and potential applications in materials science (Heras Ojea et al., 2023).


• Protein association on multimodal chromatography media.: This research explores the use of BIS-TRIS propane in multimodal chromatography to study protein interactions. The buffer′s compatibility with various chromatographic techniques enhances the understanding of protein behavior and purification processes (Muca & Antos, 2023).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable