362199
α₂-HS-Glycoprotein, Human Plasma
Synonym(s):
Fetuin, Human
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.25
Recommended Products
Assay
≥90% (SDS-PAGE)
Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: soluble
shipped in
ambient
storage temp.
−20°C
General description
Native α2-HS-glycoprotein from human plasma. Plasma protein that is also found in the extracellular matrix. Synthesized in liver and enriched in bone. Its concentration dynamically changes under various physiological conditions. Functions as an opsonin for cationic-deactivating molecules in macrophages.
Native α2-HS-glycoprotein from human plasma. Plasma protein that is also found in the extracellular matrix. Synthesized in the liver and enriched in bone. Concentration dynamically changes under various physiological conditions. Functions as an opsonin for cationic-deactivating molecules in macrophages.
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from 200 mM NaCl, 20 mM Tris-HCl, pH 8.0.
Preparation Note
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C).
Other Notes
Wang, H., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14429.
Boyan, B.D., et al. 1992. Bone Miner. 17, 263.
Yang, F., et al. 1991. Bone 12, 7.
Boyan, B.D., et al. 1992. Bone Miner. 17, 263.
Yang, F., et al. 1991. Bone 12, 7.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Edward R Smith et al.
PloS one, 8(4), e60904-e60904 (2013-04-12)
The formation of fetuin-A-containing calciprotein particles (CPP) may facilitate the clearance of calcium phosphate nanocrystals from the extracellular fluid. These crystals may otherwise seed extra-osseous mineralization. Fetuin-A is a partially phosphorylated glycoprotein that plays a critical role in stabilizing these
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