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T8266

Sigma-Aldrich

Thallium(I) acetate

≥99%

Synonym(s):

Acetic acid thallium(I) salt

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About This Item

Linear Formula:
CH3COOTl
CAS Number:
563-68-8
Molecular Weight:
263.43
Beilstein:
3693914
EC Number:
209-257-5
MDL number:
MFCD00013045
UNSPSC Code:
12352103
PubChem Substance ID:
57654707
NACRES:
NA.23

Assay

≥99%

form

powder

reaction suitability

core: thallium
reagent type: catalyst

SMILES string

CC(=O)O[Tl]

InChI

1S/C2H4O2.Tl/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

HQOJMTATBXYHNR-UHFFFAOYSA-M

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General description

Thallium (I) acetate can be prepared by dissolving thallium (III) oxide in acetic acid and acetic anhydride and stirring at 80-90oC. After filtration, the solution cooled and the product is recrystallized. A study reports that a large number of mycoplasmas and acholeplasmas can grow in its presence at concentration of 1 mg/ml.

Application

Commonly used in the laboratories as a selective element against gram-negative bacteria in selective media for the detection of mollicutes. It may be used in synthesizing thallium derivatives.

Signal Word

Danger

Hazard Statements

H300 + H330,H373,H411

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Properties and Structures of Thallium (I) Derivatives of Aromatic Diols.
El-Hadad AA, et al.
Inorganic Chemistry, 34(1), 120-123 (1995)
V Eybl et al.
Ceskoslovenska farmacie, 41(7-8), 243-245 (1992-10-01)
Experiments carried out on male mice (ICR) demonstrated a protective effect of premedication with the preparation Sho-Saiko-To (TJ 9, Tsumura and Comp.) against the hepatotoxic effects of CCl4 and T1-acetate, which were manifested by increased peroxidation of lipids and increased
R Barroso-Moguel et al.
Journal of applied toxicology : JAT, 16(5), 385-389 (1996-09-01)
A histopathological study, with a light microscope, of experimental neuromyopathy produced by thallotoxicosis was undertaken in 40 newborn Wistar rats. Treatment consisted of a single i.p. injection of an aqueous solution of 16 mg kg-1 thallium(I) acetate 1 day after
Chee-Fah Chia et al.
Annals of the New York Academy of Sciences, 1042, 523-530 (2005-06-21)
Thallium acetate is a known neurotoxic agent. In this study, we investigated the mechanisms by which thallium acetate induces cell cycle arrest and cell apoptosis in cultured LC6 glioma cells. Exposure of C6 glioma cells to thallium acetate decreased cell
T Ohyashiki et al.
Biochimica et biophysica acta, 858(2), 294-300 (1986-06-26)
The effect of alpha-tocopherol on the lipid fluidity of porcine intestinal brush-border membranes was studied using pyrene as a fluorescent probe. Addition of alpha-tocopherol to the medium decreased fluorescence intensity and lifetime, but increased the fluorescence polarization of pyrene-labeled membranes.
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