Skip to Content
Merck
All Photos(1)

Key Documents

QBD10289

Sigma-Aldrich

m-dPEG®12-MAL

Synonym(s):

Polyethylene glycol

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C32H58N2O15
CAS Number:
Molecular Weight:
710.81
MDL number:
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: sulfhydryl reactive

reagent type: linker
reactivity: thiol reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

Features and Benefits

The m-dPEG®12-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®12-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service