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A44509

Sigma-Aldrich

α-Amino-γ-butyrolactone hydrobromide

99%

Synonym(s):

(±)-α-Amino-γ-butyrolactone hydrobromide, DL-Homoserine lactone hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2 · HBr
CAS Number:
6305-38-0
Molecular Weight:
182.02
Beilstein:
4530084
EC Number:
228-614-6
MDL number:
MFCD00012723
UNSPSC Code:
12352202
PubChem Substance ID:
24890868
NACRES:
NA.22

Assay

99%

form

crystalline

color

white to light yellow

mp

220-225 °C (lit.)

application(s)

peptide synthesis

SMILES string

Br[H].NC1CCOC1=O

InChI

1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H

InChI key

MKLNTBLOABOJFZ-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Steven E A Christiaen et al.
Journal of microbiological methods, 87(2), 213-219 (2011-08-23)
A large number of Gram-negative pathogens produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Therefore, strategies to inhibit QS are promising for the control
Fumiko Taguchi et al.
Molecular plant pathology, 14(3), 279-292 (2012-11-14)
Virulence factor regulator (Vfr) is a member of the cyclic 3',5'-adenosine monophosphate (cAMP) receptor proteins that regulate the expression of many important virulence genes in Pseudomonas aeruginosa. The role of Vfr in pathogenicity has not been elucidated fully in phytopathogenic
Fiorela Nievas et al.
Sensors (Basel, Switzerland), 12(3), 2851-2873 (2012-06-28)
Bacteria of the genus Bradyrhizobium are able to establish a symbiotic relationship with peanut (Arachis hypogaea) root cells and to fix atmospheric nitrogen by converting it to nitrogenous compounds. Quorum sensing (QS) is a cell-cell communication mechanism employed by a
Cao Xu et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 51(6), 769-775 (2011-08-27)
Quorum-sensing (QS) is a regulatory mechanism with which bacteria regulate the gene expression according to their population density. Pseudomonas aeruginosa regulates the expression of multiple genes via a hierarchical quorum-sensing cascade through LasR and RhlR and their cognate signal molecules
Ariel A Romano et al.
Journal of inorganic biochemistry, 107(1), 96-103 (2011-12-20)
Bacteria use small diffusible molecules to exchange information in a process called quorum sensing (QS). An important class of quorum sensing molecules used by Gram-negative bacteria is the family of N-acylhomoserine lactones (HSL). It was recently discovered that a degradation
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