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SML3501

Sigma-Aldrich

Dehydrocorydaline

≥98% (HPLC)

Synonym(s):

13-Methylpalmatine, 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium

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5 MG
443,00 kr.
25 MG
1.790,00 kr.

443,00 kr.

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5 MG
443,00 kr.
25 MG
1.790,00 kr.

About This Item

Empirical Formula (Hill Notation):
C22H24NO4
CAS Number:
30045-16-0
Molecular Weight:
366.43
MDL number:
MFCD00887635
UNSPSC Code:
41115709
NACRES:
NA.77

443,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

CC1=C2[N+](CCC3=C2C=C(OC)C(OC)=C3)=CC4=C(OC)C(OC)=CC=C41

InChI

1S/C22H24NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-12H,8-9H2,1-5H3/q+1

InChI key

RFKQJTRWODZPHF-UHFFFAOYSA-N

Biochem/physiol Actions

Alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects
Dehydrocorydaline is an alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects. Dehydrocorydaline attenuates bone cancer pain through suppression M1 phenotype and upregulation M2 phenotype of microglia in the spinal cord.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000324594
0000196587
0000205349
0000205348

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Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype.
Huo W, Zhang Y, Liu Y, Lei Y, Sun R, Zhang W, Huang Y, Mao Y, Wang C, Ma Z, Gu X.
Molecular Pain (2018)
Zhi-Yu Yin et al.
Scientific reports, 6, 27129-27129 (2016-06-09)
Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis. Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects and that it can protect the cardiovascular system. However, there are few studies of the antinociceptive effects of DHC

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