SML0511

GNF-5

≥98% (HPLC)

• Synonym(s): N-(2-Hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
• Empirical Formula (Hill Notation): C₂₀H₁₇F₃N₄O₃
• CAS Number: 778277-15-9
• Molecular Weight: 418.37
• MDL number: MFCD16877246
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825520
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: OCCNC(=O)c1cccc(c1)-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2
• InChI: 1S/C20H17F3N4O3/c21-20(22,23)30-16-6-4-15(5-7-16)27-18-11-17(25-12-26-18)13-2-1-3-14(10-13)19(29)24-8-9-28/h1-7,10-12,28H,8-9H2,(H,24,29)(H,25,26,27)
• InChI key: IIQUYGWWHIHOCF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

GNF-5 is a BRC-Abl inhibitor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Abl page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

GNF-5 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the GNF-5 probe summary on the Chemical Probes Portal website.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3