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SAB5701987

Sigma-Aldrich

Anti-UBE4A Antibody, clone 2A5N2, Rabbit Monoclonal

Synonym(s):

UBE4A, E4, UBOX2, UFD2, ubiquitination factor E4A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

material

colorless

clone

2A5N2, monoclonal

form

liquid

mol wt

125 kDa

species reactivity

rat, human, rat

concentration

1.20 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQSDELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSD

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UBE4A(9354)

General description

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn′s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE4A (Q14139).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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