SAB4500148
Anti-Cofilin antibody produced in rabbit
affinity isolated antibody
Synonym(s):
CFL, CFL1, CFL2, Cofilin 2, Cofilin-1
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100 μG
3.170,00 kr.
3.170,00 kr.
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100 μG
3.170,00 kr.
About This Item
3.170,00 kr.
Please contact Customer Service for Availability
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 18 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CFL2(1073)
Related Categories
General description
Anti-Cofilin Antibody detects endogenous levels of total Cofilin protein.
Cofilin is a member of the actin depolymerizing factor/cofilin family. Among all members, cofilin‐1 is the predominant isoform. It is located on human chromosome 11q13.
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin.
Immunogen Range: 61-110
Immunogen Range: 61-110
Application
Anti-Cofilin antibody has been used in western blotting.
Biochem/physiol Actions
Cofilin plays an important role in actin filament remodeling that is required in chemotaxis, cell migration and invasion of tumor cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jun-Bum Park et al.
Oncotarget, 5(19), 9382-9395 (2014-09-23)
Malignant gliomas are highly proliferative and invasive neoplasms where total surgical resection is often impossible and effective local radiation therapy difficult. Consequently, there is a need to develop a greater understanding of the molecular events driving invasion and to identify
Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14
Gillett GT, et al.
Annals of Human Genetics, 60 (1996)
Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer
Satoh M, et al.
Cancer Science, 108, 795-803 (2017)
Irena Audzeyenka et al.
Journal of cellular physiology, 236(6), 4655-4668 (2020-11-28)
Insulin plays a major role in regulating glucose homeostasis in podocytes. Protein kinase G type Iα (PKGIα) plays an important role in regulating glucose uptake in these cells. Rac1 signaling plays an essential role in the reorganization of the actin
Irena Audzeyenka et al.
Biochimica et biophysica acta. Molecular cell research, 1867(8), 118723-118723 (2020-04-18)
A growing body of evidence suggests a role of proteolytic enzymes in the development of diabetic nephropathy. Cathepsin C (CatC) is a well-known regulator of inflammatory responses, but its involvement in podocyte and renal injury remains obscure. We used Zucker
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