Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.
Application
Suberic acid bis(N-hydroxysuccinimide ester) has been:
supplemented in pierce lysis buffer used for immunoprecipitation[1]
used to conjugate the oligonucleotide standards to gelatin[2]
used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers[3]
The increasing frequency of antimicrobial resistance is a problem of global importance. Novel strategies are urgently needed to understand and inhibit antimicrobial resistance gene transmission that is mechanistically related to bacterial virulence functions. The conjugative transfer of plasmids by type
Scutellarin suppresses NLRP3 inflammasome activation in macrophages and protects mice against bacterial sepsis
Cell-surface tumor marker EpCAM plays a key role in proliferation, differentiation and adhesion processes in stem and epithelial cells. It is established as a cell-cell adhesion molecule, forming intercellular interactions through homophilic association. However, the mechanism by which such interactions
Journal of immunology (Baltimore, Md. : 1950), 193(5), 2554-2564 (2014-07-30)
Epidermal Langerhans cells (eLCs) uniquely express the C-type lectin receptor langerin in addition to the HIV entry receptors CD4 and CCR5. They are among the first target cells to encounter HIV in the anogenital stratified squamous mucosa during sexual transmission.
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