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S014

Sigma-Aldrich

1-(3-Chlorophenyl)piperazine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H13ClN2·2 HCl
CAS Number:
Molecular Weight:
269.60
EC Number:
MDL number:
UNSPSC Code:
12352103
NACRES:
NA.22

SMILES string

Cl.Cl.Clc1cccc(c1)N2CCNCC2

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Iu O Fedotova et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 58(6), 75-80 (2012-01-01)
The present work was devoted to the comparative analysis of influence of chronic administration of 5-HT(2B/2C) receptors agonist - m-CPP (0,5 mg/kg, i.p.) and 5-HT(2A/2C) receptors antagonist - ketanserine (0,1 mg/kg, i.p.) for 14 days on the anxiety and depressive-like
D Karhu et al.
International journal of clinical pharmacology and therapeutics, 49(12), 730-743 (2011-11-30)
To characterize the pharmacokinetics, safety, and tolerability of an extended-release formulation of trazodone hydrochloride (HCl), Trazodone Contramid® Once-a-Day (TzCOAD) developed as scored 150-mg and 300-mg caplets for oncedaily administration. Relative bioavailability studies compared the pharmacokinetics of TzCOAD and trazodone immediate-release
Carl L Faingold et al.
Brain research, 1418, 104-110 (2011-09-17)
DBA mice are models of sudden unexpected death in epilepsy (SUDEP) that exhibit audiogenic generalized convulsive seizures (GCS), ending in death due to respiratory arrest (RA). Serotonin (5-HT) normally enhances respiration in response to elevated CO(2) levels, which occur during
Iu O Fedotova et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(1), 12-15 (2012-03-27)
Comparative study of the effects of chronic administration of 5-HT(2A/2C)-receptors agonist (m-CPP, 0.5 mg/kg, i.p.) and 5-HT(2A/2C)-receptors antagonist (ketanserine, 0.1 mg/kg, i.p.) for 14 days on the anxiety- and depression-like behavior in adult prenatally stressed female rats showed that prenatal
Saima Khaliq et al.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 22(2), 75-79 (2012-02-09)
To determine the effect of non-selective 5-HT2C antagonist mesulergine and 5-HT2C agonist mCPP (metachlorophenylpiperazine) on learning acquisition (LA), short-term memory (STM) and long-term memory (LTM). Experimental study. Department of Biochemistry, University of Karachi, from December 2009 to June 2010. Twenty-four

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