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RAB0705

Sigma-Aldrich

Human LTF / Lactotransferrin ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.96 ng/mL
standard curve range: 1.966-480 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LTF(4057)

General description

LTF (lactotransferrin) codes for a 80 kDa glycoprotein which is expressed in many tissues and organs such as mammary gland, uterus, kidney and brain and found in body fluids including tears, milk, vitreous humor and saliva. Lactotransferrin is considered pleiotropic. Lactotransferrin belongs to the transferrin family and is homologous in sequence and structure with iron binding protein. The LTF gene is mapped to human chromosome 3p21.31.
The LTF ELISA kit provides for the Quantitative measurement of Lactotransferrin in Cell Culture Supernatants, Plasma and Serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Lactotransferrin regulates the immune and inflammatory responses. Lactotransferrin is also known to be involved in bone metabolism. It might play an important role in dental osseointegration implantation. Lactotransferrin is known for its antimicrobial anti-viral, anti-fungal, anti-parasitic, anti-inflammatory and antioxidant activity. Anti-angiogenic, anti-tumor effects of this protein proves that it is a tumor suppressor. Neuronal differentiation is also an important function of lactotransferrin.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Lanctôt et al.
Journal of dairy science, 100(3), 2269-2281 (2017-01-23)
The transition from lactation to the dry period in dairy cows is a period of high risk for acquiring new intramammary infections. This risk is reduced when the involution of the mammary gland is completed. Accordingly, approaches that speed up
Theresa J Ochoa et al.
The Journal of pediatrics, 219, 118-125 (2020-02-11)
To determine the effect of bovine lactoferrin on prevention of late-onset sepsis (LOS) and neurodevelopment delay. Randomized, double-blind, controlled trial in neonates with a birth weight of 500-2000 g in 3 neonatal units in Lima, Peru, comparing bovine lactoferrin 200 mg/kg/day
B Ponchon et al.
Journal of dairy science, 100(10), 8496-8506 (2017-08-02)
The risk for a dairy cow to acquire new intramammary infections is high during the transition from lactation to the dry period, because of udder engorgement and altered immune functions. Once the gland is fully involuted, it becomes much more
L actotransferrin Gene (LTF) Polymorphisms and Dental Implant Loss: A Case?Control Association Study.
Doetzer A D, et al.
Clinical Implant Dentistry and Related Research, 17, e550-e561 (2015)
Ming-Tse Kuo et al.
International journal of molecular sciences, 22(1) (2021-01-07)
Most studies about dry eye disease (DED) chose unilateral eye for investigation and drew conclusions based on monocular results, whereas most studies involving tear proteomics were based on the results of pooling tears from a group of DED patients. Patients
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