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Key Documents

O1382

Sigma-Aldrich

Ochratoxin B

from Aspergillus ochraceus

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About This Item

Empirical Formula (Hill Notation):
C20H19NO6
CAS Number:
Molecular Weight:
369.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Pricing and availability is not currently available.

biological source

Aspergillus ochraceus

storage temp.

2-8°C

SMILES string

CC1Cc2ccc(C(=O)NC(Cc3ccccc3)C(O)=O)c(O)c2C(=O)O1

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ralf Blank et al.
The Journal of nutrition, 134(9), 2355-2358 (2004-08-31)
The mycotoxin ochratoxin A (OA) is a cause of endemic nephropathy in farm animals and humans. Reabsorption of OA along the nephron results from nonionic diffusion and by carrier-mediated mechanisms, indicating that urine alkalinization may help to accelerate OA excretion
Vasilica Lates et al.
Analytical and bioanalytical chemistry, 402(9), 2861-2870 (2012-02-15)
We report here the development of a new assay for the detection of ochratoxin A (OTA) based on the use of its dechlorinated analogue, ochratoxin B (OTB), in a displacement immunoassay. OTB was immobilised on controlled-pore glass beads followed by
Rebeca Remiro et al.
Journal of chromatography. A, 1217(52), 8249-8256 (2010-11-30)
A validated high-performance liquid chromatography (HPLC) method with fluorescence detection for the simultaneous quantification of ochratoxin A (OTA) and its analogues (ochratoxin B (OTB), ochratoxin C (OTC) and methyl ochratoxin A (MeOTA)) in red wine at trace levels is described.
Alexandra H Heussner et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(5), 827-833 (2006-12-13)
Monoclonal antibodies against ochratoxin B (OTB) were generated by immunizing Balb/c mice with OTB conjugated to keyhole limpet hemocyanin (KLH) via carbodiimide reactions with CHMC and EDAC. A stable hybridoma cell line 2F1.E10 was produced by fusion of murine splenocytes
D R Dietrich et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 53(2-3), 215-225 (2001-08-04)
Four different cell models were chosen for comparison of OTA and OTB toxicity: primary porcine (PKC), rat (RPTC) and human renal proximal epithelial cells (HKC) from both sexes and a porcine renal cell line: LLC-PK1. Culture conditions were tested and

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