Skip to Content
Merck
All Photos(1)

Key Documents

L2777

Sigma-Aldrich

Lisinopril

ACE Inhibitor

Synonym(s):

(S)-Nα-(1-Carboxy-3-phenylpropyl)-Lys-Pro

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
4.330,00 kr.

4.330,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(1)

Select a Size

Change View
1 G
4.330,00 kr.

About This Item

EC Number:
278-488-1
UNSPSC Code:
12352204
NACRES:
NA.26

4.330,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order

General description

Lisinopril is a nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor. It is used in the treatment of heart failure and hypertension. Lisinopril is an antihypertensive and anticongestive agent, like other members of its family. It is water-soluble and possesses weak chelating properties.[1][2][3][4]

Application

Lisinopril has been used as an angiotensin-converting enzyme (ACE) inhibitor:
  • in combination with spironolactone, to study their effects on cardiac and skeletal muscles in the Duchenne muscular dystrophy (DMD) mice model[5]
  • standard in in vitro ACE inhibitory assay[6]
  • as a negative control in ACE enzymatic assay[7]

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360D,H373

Hazard Classifications

Repr. 1A - STOT RE 2

Target Organs

Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
102K0964
097H0209
073H0893

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

(±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder

Sigma-Aldrich

M5391

(±)-Metoprolol (+)-tartrate salt

Losartan potassium

Supelco

61188

Losartan potassium

Angiotensin converting enzyme inhibitors: comparative structure, pharmacokinetics, and pharmacodynamics.
Thind GS
Cardiovascular Drug Reviews (1990)
P W Swaan et al.
Biochimica et biophysica acta, 1236(1), 31-38 (1995-05-24)
The affinity of three substrates for the intestinal peptide carrier is explained based on their three-dimensional (3D) structural data. The kinetic transport parameters of three ACE-inhibitors, enalapril, enalaprilat, and lisinopril, have been determined in an in vivo system using rat
E J Wallis et al.
Clinical pharmacology and therapeutics, 64(4), 439-449 (1998-11-03)
The antihypertensive response to angiotensin-converting enzyme (ACE) inhibitors may be attenuated by a compensatory decrease in atrial natriuretic factor production. If so, inhibition of atrial natriuretic factor breakdown by neutral endopeptidase (NEP) may enhance the antihypertensive effects of ACE inhibition.
Comparative Effects of Low and High Doses of the
Angiotensin-Converting Enzyme Inhibitor, Lisinopril, on
Morbidity and Mortality in Chronic Heart Failure
Milton Packer
Clinical and Investigative Medicine. Medecine Clinique Et Experimentale (2017)
R L Hamlin et al.
Journal of veterinary internal medicine, 12(2), 93-95 (1998-04-30)
This study was designed to determine the degree of inhibition of the angiotensin-converting enzyme (ACE) in 5 normal dogs given single doses of conventionally used ACE inhibitors (ACEis). In addition the time required for that inhibition to return to 50%
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service