H0540

Anti-Hepatocyte Growth Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-HGF
• MDL number: MFCD00212968
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): capture ELISA: 0.2-0.8 μg/mL; immunohistochemistry: 5-15 μg/mL; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: Q08048
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Hgf(15234)

Description

Immunogen

purified, NSO cell-derived recombinant mouse hepatocyte growth factor.

Biochem/physiol Actions

Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. The cellular effects of HGF are mediated by its receptor, c-Met, that leads to significant activation of ERK, Src/FAK, STAT3 and PI3K signaling. Various functions of the HGF/c-Met signaling include proliferation, cell survival, motility and adhesion and tissue regeneration. Apart from liver, HGF also mediates regeneration of kidney, lung and gastro-intestines.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves