D7625

2′-Deoxycytidine 5′-monophosphate sodium salt

Sigma Grade, ≥98%

• Synonym(s): Deoxycytidylic acid, dCMP
• Linear Formula: C₉H₁₂N₃O₇PNa₂
• CAS Number: 13085-50-2
• Molecular Weight: 351.16
• EC Number: 235-995-2
• MDL number: MFCD00069774
• UNSPSC Code: 41106305
• PubChem Substance ID: 24894142
• NACRES: NA.51

Properties

• biological source: microbial (fermentation)
• grade: Sigma Grade
• Assay: ≥98%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(O)=O)O2
• InChI: 1S/C9H14N3O7P.Na.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17);;
• InChI key: BLEUYVBRJBDVEH-UHFFFAOYSA-N

Description

Application

2′-Deoxycytidine 5′-monophosphate sodium salt has been used:

• in nucleoside stability studies in human renal cell carcinoma (RCC) cell line SN12C[1]
• in the cell proliferation studies of human intestinal Caco-2 cell line[2] and peripheral blood mononuclear cells (PBMCs)[3]
• as a ligand in dsDNA activation-induced cytidine deaminase crystallization[4]

2′-Deoxycytidine 5-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves