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C8605

Sigma-Aldrich

Dihydroceramide C8

98%, waxy solid

Synonym(s):

D-erythro-N-Octanoyldihydrosphingosine

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About This Item

Empirical Formula (Hill Notation):
C26H53NO3
Molecular Weight:
427.70
MDL number:
MFCD01320385
UNSPSC Code:
12352211
PubChem Substance ID:
329775180
NACRES:
NA.77

Quality Level

200

Assay

98%

form

waxy solid

color

white

solubility

ethanol: 10 mg/mL
DMF: 25 mg/mL
DMSO: 5 mg/mL

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

InChI

1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1

InChI key

LGOFBZUQIUVJFS-LOSJGSFVSA-N

Biochem/physiol Actions

Inactive form of C8 ceramide for use as a negative control.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Y W Hsu et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5388-5397 (2001-04-21)
The goal of this study was to elucidate whether triggering the sphingomyelin pathway modulates LPS-initiated responses. For this purpose we investigated the effects of N-acetylsphingosine (C(2)-ceramide) on LPS-induced production of NO and PGE(2) in murine RAW 264.7 macrophages and explored
Mike Lange et al.
Cell reports. Medicine, 2(10), 100407-100407 (2021-11-11)
Obesity, characterized by expansion and metabolic dysregulation of white adipose tissue (WAT), has reached pandemic proportions and acts as a primer for a wide range of metabolic disorders. Remodeling of WAT lipidome in obesity and associated comorbidities can explain disease

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