74134
epi-Inositol
≥98.0% (HPLC)
Synonym(s):
epi-Cyclohexanehexol
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Assay
≥98.0% (HPLC)
form
crystals
storage temp.
2-8°C
SMILES string
O[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H](O)[C@@H]1O
InChI
1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6+
InChI key
CDAISMWEOUEBRE-NIPYSYMMSA-N
Biochem/physiol Actions
epi-Inositol has regulatory effects on expression of the most highly regulated gene in the inositol biosynthetic pathway.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Akari Ozaki et al.
Journal of bioscience and bioengineering, 109(4), 337-340 (2010-03-17)
Phospholipase D-mediated synthesis of phosphatidylinositols having various inositol stereoisomers was studied. Seven inositol stereoisomers were tested, all of which were found to be substrates of the enzyme, generating the corresponding phosphatidylinositols. Based on the substrate specificity, models for the recognition
J McLaurin et al.
The Journal of biological chemistry, 275(24), 18495-18502 (2000-04-15)
Inositol has 8 stereoisomers, four of which are physiologically active. myo-Inositol is the most abundant isomer in the brain and more recently shown that epi- and scyllo-inositol are also present. myo-Inositol complexes with Abeta42 in vitro to form a small
JoAnne McLaurin et al.
Nature medicine, 12(7), 801-808 (2006-06-13)
When given orally to a transgenic mouse model of Alzheimer disease, cyclohexanehexol stereoisomers inhibit aggregation of amyloid beta peptide (Abeta) into high-molecular-weight oligomers in the brain and ameliorate several Alzheimer disease-like phenotypes in these mice, including impaired cognition, altered synaptic
A Shaldubina et al.
Molecular psychiatry, 7(2), 174-180 (2002-02-13)
Myo-inositol exerts behavioral effects in animal models of psychiatric disorders and is effective in clinical trials in psychiatric patients. Interestingly, epi-inositol exerts behavioral effects similar to myo-inositol, even though epi-inositol is not a substrate for synthesis of phosphatidylinositol. We postulated
Xiao-Long Liu et al.
Pesticide biochemistry and physiology, 164, 7-13 (2020-04-15)
Insect gustatory system plays important roles in multiple behaviors including feeding, mating, and oviposition. Gustatory receptors (GRs), located on the dendritic membrane of gustatory sensory neurons (GSNs), are crucial in peripheral coding of non-volatile compounds. However, GRs and their detailed
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