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52044

Sigma-Aldrich

Hexaethylene glycol monododecyl ether

BioXtra, ≥98.0% (TLC)

Synonym(s):

C12E6, Dodecylhexaglycol, Polyoxyethylene (6) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)6OH
CAS Number:
Molecular Weight:
450.65
Beilstein:
1715367
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

product line

BioXtra

Assay

≥98.0% (TLC)

mol wt

450.65 g/mol

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C24H50O7/c1-2-3-4-5-6-7-8-9-10-11-13-26-15-17-28-19-21-30-23-24-31-22-20-29-18-16-27-14-12-25/h25H,2-24H2,1H3

InChI key

OJCFEGKCRWEVSN-UHFFFAOYSA-N

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Other Notes

Non-ionic surfactant which effectively releases histamine from rat peritoneal mast cells

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gel filtration of solubilized systems. VII. Temperature effect on the solubilization of ethylparaben in hexaoxyethylene lauryl ether micelles.
A Goto et al.
Chemical & pharmaceutical bulletin, 32(8), 2905-2909 (1984-08-01)
S Kaneshina et al.
Biochimica et biophysica acta, 603(2), 237-244 (1980-12-12)
An aqueous solution of non-ionic surfactants becomes suddenly turbid when heated to a critical temperature, known as the cloud point, and concomitantly expands the volume. The volume expansion is caused by release of structured water molecules from the hydrophilic polyoxyethyelene
A C Donegan et al.
The Journal of pharmacy and pharmacology, 39(1), 45-47 (1987-01-01)
The rates of solubilization of a homologous series of n-alkanes (CnH2n + 2; n = 8-16) into micellar solutions of n-dodecyl hexaoxyethylene glycol ether (C12E6) have been measured at 298 K. A mechanism involving a micellar dissociation-association process previously proposed
Maiko Miyake et al.
The journal of physical chemistry. B, 112(15), 4648-4655 (2008-03-28)
Wormlike micelles of the surfactant penta-, hexa-, and heptaoxyethylene dodecyl ethers C12 E5, C12 E6, and C12 E7 were characterized by static light scattering (SLS) and dynamic light scattering (DLS) experiments to examine effects of uptake of n-dodecane on the
G Calvin et al.
Toxicology letters, 18(3), 351-357 (1983-09-01)
Oral doses (100 mg/kg/day) of a 14C-labelled branched-chain alkylpolyethoxylate [( C5H11]2CH14CH2O[CH2CH2O]6H; abbreviated [14C]A12E6) were extensively absorbed from the gastrointestinal tract of rats. During a multiple dosing regime, a proportion of 14C equivalent to one daily dose was excreted each day.

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