Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

I114

Supelco

p-Iodoclonidine hydrochloride

analytical standard, for drug analysis

Synonym(s):

2-[(2,6-Dichloro-4-iodophenyl)imino]imidazoline hydrochloride

Sign Into View Organizational & Contract Pricing

Select a Size

25 MG
478,00 kr.

478,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(1)

Select a Size

Change View
25 MG
478,00 kr.

About This Item

Empirical Formula (Hill Notation):
C9H8Cl2IN3 · HCl
CAS Number:
108294-53-7
Molecular Weight:
392.45
MDL number:
MFCD00069292
UNSPSC Code:
41116107
PubChem Substance ID:
329815344
NACRES:
NA.24

478,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white to off-white

solubility

H2O: soluble

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl[H].Clc1cc(I)cc(Cl)c1\N=C2/NCCN2

InChI

1S/C9H8Cl2IN3.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2H2,(H2,13,14,15);1H

InChI key

ULCGXOSKNHMYAX-UHFFFAOYSA-N

Gene Information

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

High affinity α2 adrenergic receptor agonist.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

P Ernsberger et al.
Neurochemistry international, 30(1), 17-23 (1997-01-01)
Imidazoline binding sites are labeled by [3H]clonidine (I1) or by [3H]idazoxan (I2). I2-sites are mitochondrial. The subcellular localization of I1-sites in brain is unknown. Crude membranes from bovine rostral ventrolateral medulla (RVLM) were further purified by discontinuous sucrose density gradient.
Y Jin et al.
Investigative ophthalmology & visual science, 35(5), 2500-2508 (1994-04-01)
This study sought to identify and characterize subtypes of alpha 2-adrenoceptors in rabbit ciliary body. Radioligand binding assays were performed with the alpha 2-agonist ligand [125I]-p-iodoclonidine ([125I]PIC) and the antagonist ligand [3H]rauwolscine. Both [125I]PIC and [3H]rauwolscine bound to a single
D R Wallace et al.
European journal of pharmacology, 258(1-2), 67-76 (1994-06-02)
Binding characteristics of alpha 2-adrenoceptors in rat cerebral cortical membranes were compared using the antagonist radioligands [3H]idazoxan, [3H]2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline ([3H]RX821002), and the partial agonist radioligand [125I]2-[2,6-(dichloro-4-iodophenyl)imino]imidazoline ([125I]iodoclonidine). With [3H]RX821002 and alpha 2-adrenoceptor subtype-selective competitors, both alpha 2A/D- and alpha 2C-adrenoceptor subtypes
M A Haxhiu et al.
Journal of cardiovascular pharmacology, 24 Suppl 1, S1-S8 (1994-01-01)
The rostral ventrolateral medulla (RVLM) is the primary region maintaining vasomotor tone, and a site of action for central antihypertensive agents. In vitro [125I]p-iodoclonidine binding studies showed that moxonidine was selective for I1-imidazoline over alpha 2-adrenergic receptors in the RVLM.
J E Piletz et al.
The Journal of pharmacology and experimental therapeutics, 279(2), 694-702 (1996-11-01)
To identify selective compounds for nonadrenergic I1-imidazoline receptors (I1), the affinities of 22 ligands for [125I]p-iodoclonidine binding have been compared at human platelet I1-imidazoline binding sites (analyzed under norepinephrine mask of alpha-2 AR) and at human alpha-2A, alpha-2B and alpha-2C
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service