SCC286
CUTLL1 Human T-cell Lymphoblastic Lymphoma Cell Line
Human
About This Item
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Product Name
CUTLL1 Human T-cell Lymphoblastic Lymphoma Cell Line,
biological source
human
packaging
vial of >1X10⁶ cells
manufacturer/tradename
Millipore
growth mode
N/A
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
storage temp.
≤ − 140°C
Application
CUTLL1 is a human T-cell lymphoblastic lymphoma cell line derived from a relapsed patient that harbors a t(7;9)(q34;q34) chromosomal translocation resulting in expression of a TCRB-NOTCH1 fusion transcript and aberrant Notch signaling (3). CUTLL1 cells demonstrate high sensitivity to gamma-secretase inhibitors, which act on the Notch pathway. CUTLL1 cells express markers of immature T-cells including CD3, CD4, CD8 and TCRαα (3).
Source:
The CUTLL1 cell line was established from pleural effusion of a relapsed 14-year-old male patient suffering from T-cell lymphoblastic lymphoma (2)
References:
1. Cancer J. 2012; 18(5): 432-8.
2. Science 2004; 306(5694): 269-71.
3. Leukemia 2006; 20(7): 1279-87.
Features and Benefits
Storage and Stability
Other Notes
Disclaimer
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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