Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.
Specificity
This antibody recognizes the near C-terminus of IL-12 alpha
Immunogen
KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.
Application
Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.
This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.
Quality
Evaluated by Western Blotting in human lymph node tissue lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.
Target description
~25 kDa observed
Linkage
Replaces: MABN1084
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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