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Supelco

SeQuant® ZIC®-cHILIC 100Å (3 µm) HPLC Columns

L x I.D. 20 mm x 2.1 mm guard Column Kit (3 pc) with coupler (1 pc)

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About This Item

UNSPSC Code:
41115709
NACRES:
SB.52

product name

SeQuant® ZIC-cHILIC 3μm 20 x 2.1 mm Guard Kit, PEEK coated guard column 3 pc with coupler 1 pc

material

PEEK-lined stainless steel column

product line

SeQuant®

feature

endcapped: no

packaging

pkg of 3 Columns with coupler 1 pc

parameter

(pH 2 - 8)
 at ≤70 °C
 max. pressure at ≤550 bar

technique(s)

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable
mass spectrometry (MS): suitable

column L × I.D.

2 cm × 2.1 mm

matrix

fully porous particle

matrix active group

ZIC-cHILIC bonding phase

particle size

3 μm

pore size

100 Å pore size

separation technique

hydrophilic interaction (HILIC)

General description

The Guard column kit contains 5 SeQuant® ZIC®-cHILIC guard columns including the fitting to connect to the analytical column.SeQuant® ZIC®-cHILIC is designed for excellent HPLC and LC-MS of polar hydrophilic compounds. This zwitterionic stationary phase with phosphorylcholine functional group provides you with complementary selectivity for easier method development for substances that have been difficult to separate by previous types of HPLC columns operated in reversed-phase or HILIC mode.SeQuant® ZIC®-cHILIC HPLC columns provide complementary selectivity to optimize separations of polar hydrophilic compounds. The columns carry a novel densely bonded, 1:1 charge-balanced phosphorylcholine functional group. As with all true zwitterionic stationary phases, straightforward and reproducible separations are achieved by hydrophilic partitioning combined with weak ionic interactions.The more accessible positive charges of SeQuant® ZIC®-cHILIC columns enable selectivity tuning in chromatography through altered interaction with anionic and cationic molecular moieties. This can be favorable in several situations, for example in the separation of labile metal complexes or highly polar and multiply charged aminoglycosides. Their extraordinary stability and minimized bleed also make SeQuant® ZIC®-cHILIC columns the preferred choice for many LC-MS applications.Learn more about the Supelco HPLC Column portfolio and Method development:Brochure: HPLC and UHPLC Column Selection Guide Brochure: A Practical Guide to HPLC - Method Development Guide

Legal Information

SeQuant is a registered trademark of Merck KGaA, Darmstadt, Germany
ZIC is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

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