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857138C

Avanti

18:2 Lyso PA

Avanti Research™ - A Croda Brand

Synonym(s):

1-(9Z,12Z-octadecadienoyl)-2-hydroxy-sn-glycero-3-phosphate (sodium salt); PA(18:2(9Z,12Z)/0:0)

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About This Item

Empirical Formula (Hill Notation):
C21H38NaO7P
CAS Number:
65528-85-0
Molecular Weight:
456.49
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-linoleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), chloroform

Assay

>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)

form

liquid

packaging

pkg of 1 × 1 mL (857138C-10mg)
pkg of 1 × 2.5 mL (857138C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (857138C-10mg)
10 mg/mL (857138C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Lysophosphatidic acid (LPA) is a lysophospholipid comprising of glycerol 3-phosphate (G3P), fatty acids, and phosphates.

Biochem/physiol Actions

18:2 Lysophosphatidic acid (LPA) is an active ingredient of gintonin, which is a bioactive ligand of ginseng. LPA is synthesized in plants by the activity of the enzyme glycerol 3-phosphate acyltransferase (GPAT). LPA is an intermediate in the synthesis of phosphatidic acid (PA) and other phospholipids. Abnormal LPA metabolism is found in children with autism.

Packaging

5 mL Clear Glass Sealed Ampule (857138C-10mg)
5 mL Clear Glass Sealed Ampule (857138C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Potential serum biomarkers from a metabolomics study of autism
Wang H, et al.
Journal of Psychiatry & Neuroscience, 41(1), 27-27 (2016)
Bioactive lipids in gintonin-enriched fraction from ginseng
Cho HJ, et al.
Journal of ginseng research (2017)
Ross Dobie et al.
Cell reports, 29(7), 1832-1847 (2019-11-14)
Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are thought to be a functionally homogeneous population. Here, we use

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