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913898

Sigma-Aldrich

Silica nanoparticles

pore size non-porous, 300 nm particle size, 5 % (w/w) in ethanol, dispersion

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica

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About This Item

Empirical Formula (Hill Notation):
SiO2
CAS Number:
7631-86-9
Molecular Weight:
60.08
MDL number:
MFCD00011232
UNSPSC Code:
12352309
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

concentration

5 % (w/w) in ethanol

particle size

300 nm

pore size

non-porous

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse nonporous silica in ethanol, with sizes varying from 150 nm to 900 nm. The high monodispersity of our particles makes them suitable for aforementioned applications.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Glutathione- and pH-responsive nonporous silica prodrug nanoparticles for controlled release and cancer therapy.
Xu Z, et al.
Nanoscale, 7, 5859-5859 (2015)
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in
Li Tang et al.
Nano today, 8(3), 290-312 (2013-09-03)
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number

Articles

Nonporous Silica Nanoparticles Applications

Nonporous SiNPs are investigated as nanocarriers for drug delivery and smart plastics due to monodispersed particles.

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