Skip to Content
Merck
All Photos(2)

Documents

799041

Sigma-Aldrich

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 25,000, lactide:glycolide 50:50

Synonym(s):

PEG-PLGA, PEG-b-PLGA

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3[C2H4O]nO[(C2H2O2)x(C3H4O2)y]mH
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

Quality Level

mol wt

PEG average Mn 5,000
PLGA average Mn 25,000

composition

lactide:glycolide 50:50

storage temp.

2-8°C

Related Categories

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Features and Benefits

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service