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725358

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

10 nm avg. part. size, 5 mg/mL in H2O

Synonym(s):

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
1317-61-9
Molecular Weight:
231.53
MDL number:
MFCD00011010
UNSPSC Code:
12352302
PubChem Substance ID:
329764149
NACRES:
NA.23

form

dispersion
nanoparticles

concentration

5 mg/mL in H2O

magnetization

>45 emu/g, at 4500Oe

avg. part. size

10 nm

particle size

9-11 nm (TEM)

density

1.00 g/mL at 25 °C

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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General description

Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Application



  • Optical resolution of ephedrine: A study explored the optical resolution of racemic ephedrine using various derivatives of tartaric acid, presenting a method that could refine the production of pharmaceutical-grade ephedrine hydrochloride (Bánhegyi et al., 2022).


  • Stereoselective forensic analysis: Supercritical fluid chromatography coupled with tandem mass spectrometry was used to perform a stereoselective analysis of ephedrine and its isomers in seized methamphetamine samples, offering insights into forensic applications of ephedrine hydrochloride (Segawa et al., 2021).


  • Chiral analysis of stimulants: A chiral high-performance liquid chromatography-tandem mass spectrometry method was applied to determine amphetamine-type stimulants, including ephedrine, in forensic samples, providing a tool for the precise separation and identification of chiral drugs (Schwelm et al., 2020).


Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Leyong Zeng et al.
Nanoscale, 5(5), 2107-2113 (2013-02-06)
Multifunctional Fe(3)O(4)-TiO(2) nanocomposites with Janus structure for magnetic resonance imaging (MRI) and potential photodynamic therapy (PDT) were synthesized, in which Fe(3)O(4) was used as a MRI contrast agent and TiO(2) as an inorganic photosensitizer for PDT. Their morphology, structure, and
Aman Khurana et al.
Radiology, 269(1), 186-197 (2013-07-16)
To determine whether intravenous ferumoxytol can be used to effectively label mesenchymal stem cells (MSCs) in vivo and can be used for tracking of stem cell transplants. This study was approved by the institutional animal care and use committee. Sprague-Dawley
Lu Zhang et al.
Nanoscale, 5(17), 7664-7684 (2013-07-24)
Superparamagnetic iron oxide nanoparticles (SPIONs) have shown great promise in biomedical applications. In this review, we summarize the recent advances in the design and fabrication of core-shell and hetero-structured SPIONs and further outline some exciting developments and progresses of these
Margarita Gutova et al.
Stem cells translational medicine, 2(10), 766-775 (2013-09-10)
Numerous stem cell-based therapies are currently under clinical investigation, including the use of neural stem cells (NSCs) as delivery vehicles to target therapeutic agents to invasive brain tumors. The ability to monitor the time course, migration, and distribution of stem
Tsung-Ju Li et al.
Biomaterials, 34(32), 7873-7883 (2013-07-24)
We present an approach for synchronizing hyperthermia and thermal-responsive local drug release. The targeting probe has a magnetite nanocrystal (Fe₃O₄@PSMA) core and a polynucleotide shell that carries 5-fluorouracil (5-FU) and anti-human epidermal growth factor receptor 2 (anti-HER2) antibody for cancer
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