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534404

Sigma-Aldrich

N-Boc-cis-4-N-Fmoc-amino-L-proline

97%

Synonym(s):

(2S,4S)-N-tert-Butoxycarbonyl-4-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C25H28N2O6
CAS Number:
Molecular Weight:
452.50
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

Assay

97%

optical activity

[α]20/D -68°, c = 1 in chloroform

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

150-154 °C (lit.)

application(s)

peptide synthesis

functional group

Boc
Fmoc

SMILES string

CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(O)=O)NC(=O)OCC2c3ccccc3-c4ccccc24

InChI

1S/C25H28N2O6/c1-25(2,3)33-24(31)27-13-15(12-21(27)22(28)29)26-23(30)32-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,30)(H,28,29)/t15-,21-/m0/s1

InChI key

UPXRTVAIJMUAQR-BTYIYWSLSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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