510122

3-(Trifluoromethoxy)phenylboronic acid

≥95%

• Synonym(s): 3-Trifluoromethoxybenzeneboronic acid
• Linear Formula: CF₃OC₆H₄B(OH)₂
• CAS Number: 179113-90-7
• Molecular Weight: 205.93
• MDL number: MFCD01320697
• UNSPSC Code: 12352103
• PubChem Substance ID: 24873478
• NACRES: NA.22

Properties

• Assay: ≥95%
• mp: 84-89 °C (lit.)
• SMILES string: OB(O)c1cccc(OC(F)(F)F)c1
• InChI: 1S/C7H6BF3O3/c9-7(10,11)14-6-3-1-2-5(4-6)8(12)13/h1-4,12-13H
• InChI key: UWDFWVLAHRQSKK-UHFFFAOYSA-N

Description

Application

Precursor commonly used in the synthesis of biologically active compounds including:

• Multisubstituted purines for use as P2X7 antagonists in the treatment of pain
• Heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
• Fluorohydroquinolineethanol as a CETP inhibitor
• Biaryl amides with muscarinic acetylcholine receptor subtype M1 agonist activity
• C2-aryl pyrrolobenzodiasepine antitumor agents
• Piperazine-bisamide for obesity treatments

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves