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4270501

Sigma-Aldrich

Novatach™ MVG GRGDSP

GRGDSP-peptide coupled high G high MW sodium alginate, guluronic acid contentguluronic acid content ≥60 %

Synonym(s):

Cell Adhesion Peptides

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100 MG
2.550,00 kr.

2.550,00 kr.

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100 MG
2.550,00 kr.

About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

2.550,00 kr.

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

form

powder

composition

guluronic acid content

guluronic acid content, ≥60%

impurities

≤100 EU/g Endotoxins

pH

5.5-8.5 (20 °C, 1% in water)

Application

State-of-the-art, ultra-purified and modified sodium alginate, grafted with RGD peptide sequences, available in 100 mg lyophilized powder vials. Novatach Peptide-coupled UP Alginates are designed to facilitate and promote interaction between cells and alginate-based scaffolds and matrices. They are useful when cell-to-matrix interactions are beneficial. The GRGDSP peptide sequence is a common example of such adhesion ligand used for MSC stem cells. The peptide alginate is available with four different alginate backbones giving flexibility to match hydrogel properties in your application. Examples of Novatach Peptide-coupled UP Alginates applications: initiator for biological interactions between alginate hydrogels and cells, encapsulation of living cells and therapeutic proteins for cell therapy medications, 3D bioprinting, foams and cell tissue scaffolds, hydrogels, advanced drug delivery, etc.

Legal Information

Product of Dupont Nutrition USA, Inc.
NOVATACH is a trademark of Dupont Nutrition USA, Inc.

Disclaimer

NOT FOR USE IN HUMANS

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Articles

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Questions

  1. この製品のproduct infimationはありますでしょうか。ユーザーガイドのような文書があると、どのように使えばよいかが分かり、製品選択がしやすくなります。 また、この製品を使って細胞の包埋培養は可能でしょうか。

    1 answer

    1. Unfortunately, a specific protocol is not available. Please see the links below to review publications that may be helpful:

      Andersen T, Auk-Emblem P, Dornish M. 3D Cell Culture in Alginate Hydrogels. Microarrays (Basel). 2015 Mar 24;4(2):133-61. doi: 10.3390/microarrays4020133. PMID: 27600217; PMCID: PMC4996398.
      Lee KY, Mooney DJ. Alginate: properties and biomedical applications. Prog Polym Sci. 2012 Jan;37(1):106-126. doi: 10.1016/j.progpolymsci.2011.06.003. PMID: 22125349; PMCID: PMC3223967.

      Additional information can be supplied by our Technical Service team who can assist you further. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquires" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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