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279927

Sigma-Aldrich

(1R,5S)-(+)-2-Oxabicyclo[3.3.0]oct-6-en-3-one

99%

Synonym(s):

(1R,5S)-2-Oxabicyclo[3.3.0]oct-6-en-3-one, (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-1-oxapentalen-2-one, (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one

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About This Item

Empirical Formula (Hill Notation):
C7H8O2
CAS Number:
Molecular Weight:
124.14
MDL number:
UNSPSC Code:
12352103

Assay

99%

optical activity

[α]20/D +102.5°, c = 1 in methanol

mp

45-48 °C (lit.)

SMILES string

O=C1C[C@H]2C=CC[C@H]2O1

Application

Building block for the synthesis of carbocyclic nucleosides.

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Akella, L.B. Vince, R.
Tetrahedron, 52, 8407-8407 (1996)
Hagai Tavori et al.
Bioorganic & medicinal chemistry, 16(15), 7504-7509 (2008-06-24)
Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate remain elusive. PON1 hydrolyzes organophosphates, arylesters and lactones, whereas the

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