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257788

Sigma-Aldrich

Centrophenoxine hydrochloride

99%

Synonym(s):

(4-Chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester hydrochloride, 2-(Dimethylamino)ethyl 4-chlorophenoxyacetate hydrochloride, Meclofenoxate hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16ClNO3 · HCl
CAS Number:
3685-84-5
Molecular Weight:
294.17
EC Number:
222-975-3
MDL number:
MFCD00012533
UNSPSC Code:
12352101
PubChem Substance ID:
329752824

Assay

99%

SMILES string

Cl.CN(C)CCOC(=O)COc1ccc(Cl)cc1

InChI

1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H

InChI key

FIVHOHCAXWQPGC-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Precautionary Statements

P261 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
13707JN

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Punita Bhalla et al.
Experimental gerontology, 40(10), 801-806 (2005-09-03)
The debilitating consequences of age-related brain deterioration are widespread and extremely costly in terms of quality of life and longevity. Free radical induced damage is thought to be responsible, at least in part, for the degenerative effects of aging. This
[Increase of human resistance to the effects of high ambient temperatures by using drugs].
V A Pastushenkov et al.
Meditsina truda i promyshlennaia ekologiia, (9)(9), 39-42 (1995-01-01)
Bimla Nehru et al.
Molecular and cellular biochemistry, 290(1-2), 185-191 (2006-09-14)
Aluminium is one of the most studied neurotoxin, and its effects on nervous system are both structural and functional, involving various regions of brain. Aluminium toxicity is known to have multiple mechanisms of action in the central nervous system. Affinity
D Sharma et al.
Indian journal of experimental biology, 33(5), 365-368 (1995-05-01)
Age-related changes in the acetylcholinesterase activity were measured in the hippocampus, brain stem and cerebellum of rats (aged 4, 8, 16 and 24 months). The age-dependent decrease in the enzyme activity first appeared in the hippocampus; the brain stem was
Jian-Jun Zou et al.
Clinical therapeutics, 30(9), 1651-1657 (2008-10-09)
Meclofenoxate hydrochloride is a psychostimulant in the nootropic agent group available in capsule and tablet formulations approved for traumatic cataphora, alcoholic poisoning, anoxia neonatorum, and children's enuresis in China. Although these 2 generic formulations are marketed in China, information regarding
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