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16905

Sigma-Aldrich

Fmoc-D-Ile-OH

≥96.0% (HPLC), for peptide synthesis

Synonym(s):

Fmoc-D-isoleucine

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About This Item

Empirical Formula (Hill Notation):
C21H23NO4
CAS Number:
143688-83-9
Molecular Weight:
353.41
MDL number:
MFCD00080291
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57647593
NACRES:
NA.26

product name

Fmoc-D-Ile-OH, ≥96.0% (HPLC)

Assay

≥96.0% (HPLC)

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

SMILES string

CC[C@@H](C)[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m1/s1

InChI key

QXVFEIPAZSXRGM-BFUOFWGJSA-N

General description

Fmoc-D-Ile-OH is an amino acid in which Fmoc is a protected form of D-Isoleucine.

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Binu Jacob et al.
Amino acids, 48(5), 1241-1251 (2016-01-23)
Sheep myeloid antimicrobial peptide-29 (SMAP-29) is a cathelicidin-related antimicrobial peptide derived from sheep myeloid cells. In order to investigate the effects of L-to-D-amino acid substitution in SMAP-29 on bacterial selectivity, membrane interaction and anti-inflammatory activity, we synthesized its two D-enantiomeric
Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus
Torres-Larios A, et al.
European Journal of Biochemistry, 267(16), 5023-5031 (2000)
Andreas Pech et al.
Nucleic acids research, 45(7), 3997-4005 (2017-02-06)
Biological evolution resulted in a homochiral world in which nucleic acids consist exclusively of d-nucleotides and proteins made by ribosomal translation of l-amino acids. From the perspective of synthetic biology, however, particularly anabolic enzymes that could build the mirror-image counterparts

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