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161101

Sigma-Aldrich

O,O′-Bis(trimethylsilyl)thymine

97%

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About This Item

Empirical Formula (Hill Notation):
C11H22N2O2Si2
CAS Number:
7288-28-0
Molecular Weight:
270.48
MDL number:
MFCD00053571
UNSPSC Code:
12352100
PubChem Substance ID:
24849905
NACRES:
NA.22

Assay

97%

form

solid

bp

127-130 °C/18 mmHg (lit.)

mp

73-75 °C (lit.)

SMILES string

Cc1cnc(O[Si](C)(C)C)nc1O[Si](C)(C)C

InChI

1S/C11H22N2O2Si2/c1-9-8-12-11(15-17(5,6)7)13-10(9)14-16(2,3)4/h8H,1-7H3

InChI key

DRNUNECHVNIYHQ-UHFFFAOYSA-N

Application

O,O′-Bis(trimethylsilyl)thymine is a reactive intermediate for the preparation of nucleosides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mark Lazari et al.
EJNMMI research, 3(1), 52-52 (2013-07-16)
Automated radiosynthesizers are vital for routine production of positron-emission tomography tracers to minimize radiation exposure to operators and to ensure reproducible synthesis yields. The recent trend in the synthesizer industry towards the use of disposable kits aims to simplify setup
Angewandte Chemie (International Edition in English), 8, 976-976 (1969)
A general synthesis of pyrimidine nucleosides.
U Niedballa et al.
Angewandte Chemie (International ed. in English), 9(6), 461-462 (1970-06-01)
A NEW SYNTHETIC METHOD OF NUCLEOSIDES.
T NISHIMURA et al.
Chemical & pharmaceutical bulletin, 11, 1470-1472 (1963-11-01)
Studies on synthetic nucleosides. I. Trimethylsilyl derivatives of pyrimidines and purines.
T Nishimura et al.
Chemical & pharmaceutical bulletin, 12(3), 352-356 (1964-03-01)

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