155241

1-Methyl-2-piperidinemethanol

98%

• Synonym(s): 2-Hydroxymethyl-1-methylpiperidine, NSC 45464
• Empirical Formula (Hill Notation): C₇H₁₅NO
• CAS Number: 20845-34-5
• Molecular Weight: 129.20
• EC Number: 244-078-6
• MDL number: MFCD00006494
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849505
• NACRES: NA.22

Properties

• Assay: 98%
• refractive index: n20/D 1.4823 (lit.)
• bp: 79-80 °C/7 mmHg (lit.)
• density: 0.984 g/mL at 25 °C (lit.)
• SMILES string: CN1CCCCC1CO
• InChI: 1S/C7H15NO/c1-8-5-3-2-4-7(8)6-9/h7,9H,2-6H2,1H3
• InChI key: HXXJMMLIEYAFOZ-UHFFFAOYSA-N

Description

General description

The standard molar energy of combustion of 1-Methyl-2-piperidinemethanol has been studied[1].

Application

Reactant for synthesis of:
Selective MCH1R antagonists
Human GnRH receptor antagonists
Dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor 1 inhibitors
Radioiodinatable brain imaging agents for CB1 cannabinoid receptor
GABAA receptor agonists at the α3 subunit
Carbamates and N-alkylimidazoles from reaction of carbonyldiimidazoles with alcohols

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 177.8 °F - closed cup
• Flash Point(C): 81 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves