SML2573
MitoCDNB
≥98% (HPLC)
Synonym(s):
[4-(5’-Chloro-2’,4’-dinitrophenylamino)but-1-yl]triphenylphosphonium methanosulfonate
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C29H29ClN3O7PS
Molecular Weight:
630.05
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Assay
≥98% (HPLC)
form
powder
color
white to very dark brown
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
MitoCDNB is a mitochondrially selective inactivator of mitochondrial thiol redox homeostasis in isolated cells and in vivo. MitoCDNB selectively depletes the mitochondrial reduced glutathione (GSH) pool by formation of MitoGSDNB and dramatically increasing absorbance at 328 nm. It directly inhibits mitochondrial thioredoxin TrxR2 and peroxiredoxin 3.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Lee M Booty et al.
Cell chemical biology, 26(3), 449-461 (2019-02-05)
Mitochondrial glutathione (GSH) and thioredoxin (Trx) systems function independently of the rest of the cell. While maintenance of mitochondrial thiol redox state is thought vital for cell survival, this was not testable due to the difficulty of manipulating the organelle's
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service